The Gravitostat Regulates Fat Mass in Obese Male Mice While Leptin Regulates Fat Mass in Lean Male Mice
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چکیده
منابع مشابه
Body weight homeostat that regulates fat mass independently of leptin in rats and mice
Subjects spending much time sitting have increased risk of obesity but the mechanism for the antiobesity effect of standing is unknown. We hypothesized that there is a homeostatic regulation of body weight. We demonstrate that increased loading of rodents, achieved using capsules with different weights implanted in the abdomen or s.c. on the back, reversibly decreases the biological body weight...
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Pharmacokinetics of leptin in mammals has not been studied in detail and only one study has examined more than one time point in non-mutant mice and this was in a female mice. This is the first study to describe leptin distribution over a detailed time course in normal male mice. A physiologic dose (12 ng) of radiolabelled leptin was injected into adult male mice via the lateral tail vein and t...
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3 Department of Endocrinology, Affiliated Hospital of Weifang Medical University, Weifang, 8 China 9 * Corresponding author 10 Xiaodong Sun 11 Department of Endocrinology, Affiliated Hospital of Weifang Medical University, 2428 Yuhe 12 Road, Weifang, Shandong, 261031, China 13 Email: [email protected] Tel (086)18653625906 14 15 Running title: Irisin improves endothelial function 16 17 18 19 20...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2018
ISSN: 1945-7170
DOI: 10.1210/en.2018-00307